Capability Verification of the Beam Delivery System in the Superficially-Placed Tumor Therapy Terminal at HIRFL

  • The passive beam delivery system in the superficially-placed tumor therapy terminal at Heavy Ion Research Facility in Lanzhou (HIRFL), which includes two orthogonal dipole magnets as scanning system, a motor-driven energy degrader as range-shifter, series of ridge filters as range modulator and a multileaf collimator, is introduced in detail. The capacities of its important components and the whole system have been verified experimentally. The tests of the ridge filter for extending Bragg peak and the range shifter for energy adjustment show both work well. To examine the passive beam delivery system, a beam shaping experiment were carried out, simulating a three-dimensional (3D) conformal irradiation to a tumor. The encouraging experimental result confirms that 3D layer-stacking conformal irradiation can be performed by means of the passive system. The validation of the beam delivery system establishes a substantial basis for upcoming clinical trial for superficially-placed tumors with heavy ions in the therapy terminal at HIRFL.
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  • [1] . Kraft G. Strahlenlher Onkol, 1990, 166: 1-132. Hishikawa Y, Kagawa K et al. Ther. Radiol. Oncol, 2002,14: 73-773. LI Qiang, WEI Zeng-Quan et al. Nuclear Physics Review,2001, 18(2): 109-115(in Chinese)(李强,卫增泉等.原子核物理评论,2001,18(2): 109-115)4. Tatsuaki Kanai. Proceedings of NIRS International Semi-nar on the Application of Heavy Ion Acceleration to Radi-ation Therapy of Cancer. NIRS, Chiba, Japan, 1994. 15. Kraft G. Progresses in Particle and Nuclear Physics, 2000,45: 473-5446. ZHU Kun, ZHANG Jin-Quan et al. Nuclear Physics Re-view, 2003, 20(3): 197-200(in Chinese)(朱昆,张金泉等.原子核物理评论,2003, 20(3): 197-200)7. CHU W T, Ludewigt B A, Renner T R. Rev. Sci. Instrum.,1993, 64(8): 2088-20898. DAI Zhong-Ying, LI Qiang et al. HEP NP, 2006, 30(9):920-9249. Scholz M. Bull Cancer/Radiother, Elsevier, Paris, 1996,83(1): 50-5410. Urie M, Goitein M, Wagner M. Phys. Med. Biol., 1984, 29:55311. CHU W, Ludewigt B A, Renner T. Rev, Sci. Instruments,1993, 63: 205512. The Proton Medical Research Center. University ofTsukuba, online: www.pmrc.tsukuba.ac.jp13. Gottschalk B, Koehler A M, Wagner M. Upstream Scatter-ing Modulation in Proton Therapy Beams. PSI-Report 69.Proc. of the Int. Heavy Particle Therapy Workshop. PSI,Villigen: Switzerland, 198914. Th. Haberer. Treatment Delivery Principles for Ion Ther-apy Final Version for ENLIGHT WP 3.1 GSI. Darmstadt,Germany, 200315. Endo M, Koyama-Ito H, Minohara S et al. The Radiol.Oncol., 1996, 8: 231-23816. XIE Hong-Mei, WEI Zeng-Quan, LI Wen-Jian. NuclearTechniques, 1997, 20(4): 230-234(in Chinese)(颉红梅,卫增泉,李文建.核技术,1997, 20(4): 230-234)17. Carturight G. ShirkE. Nucl. Instrum. Methods, 1978, 153:457-46018. LI Qiang. Mutagenic Consequences of the Space Environ-ment, Cospar Colloquium. Xi'an, China, 2006. 51-52
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DAI Zhong-Ying, LI Qiang, XIAO Guo-Qing, JIN Xiao-Dong and YAN Zheng. Capability Verification of the Beam Delivery System in the Superficially-Placed Tumor Therapy Terminal at HIRFL[J]. Chinese Physics C, 2007, 31(7): 655-659.
DAI Zhong-Ying, LI Qiang, XIAO Guo-Qing, JIN Xiao-Dong and YAN Zheng. Capability Verification of the Beam Delivery System in the Superficially-Placed Tumor Therapy Terminal at HIRFL[J]. Chinese Physics C, 2007, 31(7): 655-659. shu
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Received: 2006-10-16
Revised: 2006-11-14
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Capability Verification of the Beam Delivery System in the Superficially-Placed Tumor Therapy Terminal at HIRFL

    Corresponding author: DAI Zhong-Ying,
  • Institute of Modern Physics, Chinese Academy of Sciences, Lanzhou 730000, China2 Graduate University of Chinese Academy of Sciences, Beijing 100049, China

Abstract: The passive beam delivery system in the superficially-placed tumor therapy terminal at Heavy Ion Research Facility in Lanzhou (HIRFL), which includes two orthogonal dipole magnets as scanning system, a motor-driven energy degrader as range-shifter, series of ridge filters as range modulator and a multileaf collimator, is introduced in detail. The capacities of its important components and the whole system have been verified experimentally. The tests of the ridge filter for extending Bragg peak and the range shifter for energy adjustment show both work well. To examine the passive beam delivery system, a beam shaping experiment were carried out, simulating a three-dimensional (3D) conformal irradiation to a tumor. The encouraging experimental result confirms that 3D layer-stacking conformal irradiation can be performed by means of the passive system. The validation of the beam delivery system establishes a substantial basis for upcoming clinical trial for superficially-placed tumors with heavy ions in the therapy terminal at HIRFL.

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