Medical application of diffraction enhanced imaging in mouse liver blood vessels

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ZHANG Xi, YUAN Qing-Xi, YANG Xin-Rong, LI Hai-Qing, CHEN Yu, CHEN Shao-Liang, ZHU Pei-Ping and HUANG Wan-Xia. Medical application of diffraction enhanced imaging in mouse liver blood vessels[J]. Chinese Physics C, 2009, 33(11): 986-990. doi: 10.1088/1674-1137/33/11/011
ZHANG Xi, YUAN Qing-Xi, YANG Xin-Rong, LI Hai-Qing, CHEN Yu, CHEN Shao-Liang, ZHU Pei-Ping and HUANG Wan-Xia. Medical application of diffraction enhanced imaging in mouse liver blood vessels[J]. Chinese Physics C, 2009, 33(11): 986-990.  doi: 10.1088/1674-1137/33/11/011 shu
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Received: 2008-12-18
Revised: 2009-04-03
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Medical application of diffraction enhanced imaging in mouse liver blood vessels

    Corresponding author: ZHANG Xi,

Abstract: 

Neovascularization is correlative with many processes of diseases, especially for tumor growth, invasion, and metastasis. What is more, these tumor microvessels are totally different from normal vessels in morphology. Therefore, observation of the morphologic distribution of microvessels is one of the key points for many researchers in the field. Using diffraction enhanced imaging (DEI), we observed the mirocvessles with diameter of about 40 μm in mouse liver. Moreover, the refraction image obtained from DEI shows higher image contrast and exhibits potential use for medical applications.

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